The Sino-US trade friction is the top uncertainty faced by the current world economy. This paper, by calculating the employment data of China's manufacturing industry, analyzes the impacts of globalization on the employment of the Sino-US manufacturing industry, and the causes of the Sino-US trade friction and its impacts on the manufacturing employment in China. In addition, positive suggestions are also proposed. The result of this study indicates that if the current US trade threat took effect, over 200, 000 jobs in China’s manufacturing industry would be reduced. Compared with the annual increase of 10 million jobs in China, this effect is controllable.