This paper, based on 1912 valid questionnaire surveys of 21 colleges in Liaoning province, verifies the influence of individual factors, family factors, and social factors on college graduates entrepreneurship. The result of the study shows that among the individual factors, demographic characteristics (gender, one-child, the place of registered permanent residence, the source of students, the college type, and their majors), entrepreneurial environment cognition, and entrepreneurial mindset have a significant impact on college graduates entrepreneurial intention; among the family factors, the father's career, the mother's education and the family income have a significant impact on their entrepreneurial intention; Of the social factors, the guidance of public opinions and the employment pressure has a positive effect on their entrepreneurial intention. The college's entrepreneurial guidance and propaganda of college's entrepreneurial policy, however, have no effect on college graduates entrepreneurial intention. Hence, it suggests that activating college graduates self-employment enthusiasm and promoting their self-employment success should be set about from the following aspects such as raising their self-employment quality and ability, developing entrepreneurship education, improving entrepreneurship environment, perfecting entrepreneurial support policies, and strengthening the propaganda of entrepreneurial policy.