With the wide application of artificial intelligence (AI) on talents management, how to realize their value by developing talents is still the key to exploring the use of AI. To a certain extent, the formation of talent empowerment system provides an effective and intelligent tool for organizing talents development. This paper, by pointing out the construction of talent empowerment system is a new opportunity for talents management and development in the era of AI, introduces the connotation and theoretical basis of the talent empowerment system, and analyzes the universal applicability of talent empowerment system and its use in the human resource management in enterprises.